Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 250-195-3 | CAS number: 30431-54-0
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- Model or submodel name:
Nonlinear classification ANN QSAR Model for prenatal developmental toxicity study
Model version: 08.03.2011
All descriptor values for bis(3,4,6-trichloro-2-pentoxycarbonylphenyl) oxalate fall in the applicability domain (training set value ±30%).
The prediction reliability in terms of classification is estimated as 88 %.
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- Prenatal developmental toxicity of bis(3,4,6-trichloro-2-pentoxycarbonylphenyl) oxalate. Non-linear QSAR (ANN) assessment.
- Year:
- 2 018
- Bibliographic source:
- Nonlinear classification ANN QSAR Model for prenatal developmental toxicity study Model version: 08.03.2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on CSA R.6
Test material
- Reference substance name:
- Bis(2,4,5-trichloro-6-carbopentoxyphenyl) oxalate
- EC Number:
- 250-195-3
- EC Name:
- Bis(2,4,5-trichloro-6-carbopentoxyphenyl) oxalate
- Cas Number:
- 30431-54-0
- Molecular formula:
- C26H24Cl6O8
- IUPAC Name:
- pentyl 2,3,5-trichloro-6-[(2-oxo-2-{3,4,6-trichloro-2-[(pentyloxy)carbonyl]phenoxy}acetyl)oxy]benzoate
1
Test animals
- Species:
- other: data from QSAR
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Key result
- Remarks on result:
- other: non-toxic from QSAR
Results (fetuses)
Effect levels (fetuses)
- Key result
- Remarks on result:
- other: non-toxic, from QSAR
Overall developmental toxicity
- Key result
- Developmental effects observed:
- no
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
