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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1991
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 6341 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea))
Deviations:
no
GLP compliance:
not specified
Analytical monitoring:
no
Remarks:
In the other aquatic toxicity tests, similar concentrations were used and analytically monitored. The concentrations were proved stable over at least 3 days. Therefore, it can be reasonably assumed that B2A concentrations were stable in this test as well.
Vehicle:
no
Details on test solutions:
Stock solution was prepared at 72.2 g/L in test medium.
Test organisms (species):
Daphnia magna
Details on test organisms:
Daphnia were less than 24h old and fed with Selenastrum capricornotum.
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
None.
Hardness:
Not specified.
Test temperature:
Not specified
pH:
Not specified
Dissolved oxygen:
c.a. 7 mg/L
Salinity:
Freshwater.
Conductivity:
Not specified
Nominal and measured concentrations:
Not specified
Details on test conditions:
Not specified
Reference substance (positive control):
yes
Remarks:
Potassium dichromate
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
37.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Details on results:
For mobility after 48 hours, EC0 was < 3.6 mg/L and EC100 was > 65 mg/L. EC50 was 37.2 mg/L.
Results with reference substance (positive control):
For mobility after 24 hours, EC50 was 0.95 mg/L with potassium dichromate.
Reported statistics and error estimates:
Not detail reported.
Validity criteria fulfilled:
yes
Conclusions:
48h-EC50 was determined as 37.2 mg/L for mobility.
Executive summary:

A short-term toxicity test was performed on daphnia according to ISO 6341 standard. After 48 hours exposure to graded concentrations of sec-butylamine, EC50 was determined as 37.2 mg/L for mobility.

Description of key information

A short-term toxicity test was performed on daphnia according to ISO 6341 standard. After 48 hours exposure to graded concentrations of sec-butylamine, EC50 was determined as 37.1 mg/L for mobility.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
37.1 mg/L

Additional information