1,3-bis(hydroxymethyl)urea

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2017-03-20 to 2017-07-10

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

118.56 °C

Decomposition:

yes

Decomp. temp.:

118.56 °C

Sublimation:

no

Pre-Test

The capillary tube containing the test item was set into the block at 18.8 °C. The block was heated until melting started. At 125 °C the test item began to melt and at 135 °C it was completely melted to a clear colourless liquid and began to boil. After cooling down no test item was in the capillary. The test item melted under decomposition.

Security Pre-test for the DSC instrument

The lid of the crucible was bloated and at the outside two black points were visible after reaching a temperature of 420 °C. After further heating to 600 °C and cooling down the crucible was the same as after reaching 420 °C. The weight was recorded with 34.06 mg after reaching 420 °C and 33.68 mg after reaching 600 °C.

Conclusions:

The melting point under decomposition referring to the pre-test was determined under these circumstances as the endothermic event with 118.56 ± 0.35 °C (391.71 ± 0.35 K).

Executive summary:

The determination of the melting point of the test item was performed via DSC (differential scanning calorimetry) according to OECD TG 102 and EC 440/2008 Method A.1. In all runs one event was detected. The event is endothermic and is stated as the melting point. The melting point under decomposition referring to the pre-test was determined under these circumstances as the endothermic event with 118.56 ± 0.35 °C (391.71 ± 0.35 K). The test item decomposes right after melting, thus, the decomposition temperature is stated as 118.56 °C.

Description of key information

The melting point of the test item was determined to be 118.56 °C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

118.56 °C

Additional information

The determination of the melting point of the test item was performed via DSC (differential scanning calorimetry) according to OECD TG 102 and EC 440/2008 Method A.1 (reference 4.2-1). In all runs one event was detected. The event is endothermic and is stated as the melting point. The melting point under decomposition referring to the pre-test was determined under these circumstances as the endothermic event with 118.56 ± 0.35 °C (391.71 ± 0.35 K). The test item decomposes right after melting, thus, the decomposition temperature is stated as 118.56 °C.