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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24 October - 9 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
Qualifier:
according to
Guideline:
other: CIPAC MT 187: Particle Size Analysis by Laser Diffraction
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: RY-95-001
- Expiration date of the lot/batch: July 01, 2022

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: ambient temperature (10°C to 30°C), protected from light
Mass median aerodynamic diameter:
43.6 µm
Percentile:
D10
Mean:
12.4 µm
Remarks on result:
other: st.dev. not provided
Percentile:
D90
Mean:
105.9 µm
Remarks on result:
other: st.dev. not provided

The test item consisted of opaque, spherical particles. The particle size distribution showed a polymodal distribution with a small shoulder at approx. 3 µm. The maximum was observed at approximately 50 µm. For spherical, nonporous particles of unit density D50 is the same as the Mass Median Aerodynamic Diameter (MMAD).

Conclusions:
The median particle size D50, i.e. MMAD, of the test item deduced from the particle size distributions was 43.6 μm.
Executive summary:

The median particle size D50, i.e. MMAD, of the test item deduced from the particle size distributions was 43.6 μm.

The particle size D10 of the test item deduced from the particle size distributions was 12.4 μm.

The particle size D90 of the test item deduced from the particle size distributions was 105.9 μm.

Description of key information

The median particle size D50, i.e. MMAD, of the test item deduced from the particle size distributions was 43.6 μm.

Additional information

The median particle size D50, i.e. MMAD, of the test item deduced from the particle size distributions was 43.6 μm.

The particle size D10 of the test item deduced from the particle size distributions was 12.4 μm.

The particle size D90 of the test item deduced from the particle size distributions was 105.9 μm.