Registration Dossier
Registration Dossier
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EC number: 289-991-0 | CAS number: 90052-75-8
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Based on all the available information, toxicity to sediment organisms is not expected to be of concern.
Key value for chemical safety assessment
Additional information
No experimental data evaluating the toxicity to sediment organisms are available for 2-octyldodecyl 12-[(1-oxooctadecyl)oxy]octadecanoate (CAS 90052-75-8). However, only negligible discharge to environmental water bodies is expected to occur via sewage treatment plants (STPs) due to: a) the ready biodegradability and b) the high adsorption properties of the substance, resulting in an effective removal in sewage treatment plants. Whatever fraction reaches the water compartment is expected to undergo rapid and ultimate degradation and the remainder will adsorb to organic soil and sediment particles where sediment organisms are potentially exposed via feed and contact with suspended organic particles. However, based on the physico-chemical properties, the bioavailability of the substance is expected to be low due to the strong binding behaviour. Therefore, chronic exposure of sediment organisms is unlikely. Furthermore, the substance is not acutely toxic to aquatic organisms up to the limit of water solubility.
Based on all the available information, toxicity to sediment organisms is therefore not expected to be of concern.
Intrinsic properties and fate
2-octyldodecyl 12-[(1-oxooctadecyl)oxy]octadecanoate (CAS 90052-75-8) is readily biodegradable. According to the Guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA, 2017), readily biodegradable substances can be expected to undergo rapid and ultimate degradation in most environments, including biological STPs. Therefore, only low concentrations of this substance are expected to be released into the environment, if at all.
Furthermore, 2-octyldodecyl 12-[(1-oxooctadecyl)oxy]octadecanoate (CAS 90052-75-8) has an estimated log Koc of > 5.0 and is poorly soluble in water (< 0.05 mg/L, 20 °C). The guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA, 2017) states that once insoluble chemicals enter a standard STP, they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will get in contact with activated sludge organisms. Thus, discharge into the aqueous/sediment compartment is likely negligible and chronic exposure of sediment organisms is improbable.
Aquatic ecotoxicity
According to the available short-term toxicity data for fish, aquatic invertebrates and algae, it can be expected that Isohexadecyl 12-[(1-oxooctadecyl)oxy]octadecanoate (CAS 97338-28-8) will not cause acute toxicity in aquatic organisms up to the limit of water solubility (< 1.39 µg/L). Chronic effects on the reproduction of Daphnia magna were observed in a long-term toxicity test. However, the Chemical Safety Assessment does not indicate a need for further investigations. According to Annex XI, Section 3 of Regulation (EC) No 1907/2006 toxicity testing with sediment organisms is deemed not necessary. The release rates to wastewater during mthe life cycle of the substance are negligible. The environmental exposure assessment for the substance indicates no risk for the aquatic and sediment compartment (all RCR< 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).
Metabolism/Bioaccumulation
If absorption by aquatic organisms should occur, 2-octyldodecyl 12-[(1-oxooctadecyl)oxy]octadecanoate (CAS 90052-75-8) is expected to be enzymatically hydrolyzed by carboxylesterased into the corresponding free fatty acid and alcohol components. The metabolism of the hydrolysis products is well established and not of concern in terms of bioaccumulation (for further information, see chapter 5.3 of the technical dossier). In consideration of all the available information, it is concluded that the potential for bioaccumulation is low.
Conclusion
Due to ready biodegradability and high adsorption, only negligible concentrations of the substance are expected to be discharged into water bodies, if at all. Whatever fraction is released is expected to rapidly degrade or adsorb to particles of sediment and soil where sediment organisms are potentially exposed via feed and contact with suspended organic particles. However, based on the physico-chemical properties of the substance (i.e. strong binding behaviour), bioavailability is expected to be low. If uptake should occur, extensive and fast biotransformation of the substance and its metabolites is expected by the action of carboxlesterases.
Furthermore in accordance with Annex IX, column 2 of Regulation (EC) No 1907/2006, toxicity testing with sediment organisms does not need to be conducted as the Chemical Safety Assessment does not indicate a need for further investigations. According to Annex XI, Section 3 of Regulation (EC) No 1907/2006 toxicity testing with sediment organisms is deemed not necessary. The release rates to wastewater during the life cycle of the substance are negligible. The environmental exposure assessment for the substance indicates no risk for the aquatic and sediment compartment (all RCR< 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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