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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Guideline:
other: company specific method
Principles of method if other than guideline:
Laser diffraction after dry dispersion of the test substance.
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
NC 2000 S
batch GG151024 03; BIW 13
Mass median aerodynamic diameter:
212.09 µm
Percentile:
D50
Mean:
212.09 µm
St. dev.:
192.45
Remarks on result:
other: Standard deviation value considered to be best represented by the one of SMD
Key result
Percentile:
D10
Mean:
124.85 µm
St. dev.:
192.45
Remarks on result:
other:
Remarks:
presented by the one of SMD
Percentile:
D90
Mean:
345.86 µm
St. dev.:
192.45
Remarks on result:
other:
Remarks:
presented by the one of SMD

Cumulative distribution

 x0/µm

 Q3/%  x0/µm  Q3/%  x0/µm  Q3/%  x0/µm  Q3/%
4.5 0 18.5 0 75 0.89 305 82.86
5.5 0 21.5 0 90 2.19 365 93.34
6.5 0 25 0 105 4.62 435 99.25
7.5 0 30 0 125 10.04 515 99.98
9 0 37.5 0 150 19.97 615 100
11 0 45 0.05 180 34.32 735 100
13 0 52.5 0.13 215 51.42 875 100
15.5 0 62.5 0.36 255 68.27
Conclusions:
The mass median diameter of the melam sample is 212.09 µm.
Executive summary:

A laser diffraction particle sizer, HELOS (H3982) provided with a RODOS dispersion device, was used to determine the particle size distribution. A Vibri feeder dosing system was used. The mass median diameter of the NC2000S sample was measured as 212.09 µm. The D10 was measured as 124,85µm. The material is not considered as nano and probably not entering the alveolar region.

Description of key information

 The material is not considered as nano and probably not entering the alveolar region

Additional information

Samples of NC2000S had a mean particle size diameter of 212.09 µm.