1,4-naphthoquinone

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

not specified

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline followed

Principles of method if other than guideline:

Data detailed in the International Chemical Safety Card (ICSC) for 1,4-Naphthoquinone. These cards are meant as a way of summarising essential information on chemical substances; and were jointly developed by the IPCS and the European Comission.

The cards are then peer-reviewed by a committee consisting of internationally-recognized experts who take into account advice given by manufacturers, workers' representatives and poisons centres.

The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative values for the properties under investigation.

Based on the above information, although full experimental details are unknown, the values presented here are acceptable as they are considered to be from a reliable secondary source of phys chem. data.

GLP compliance:

not specified

Type of method:

other: unknown method

Temp.:

50 °C

Vapour pressure:

2.6 Pa

Conclusions:

The test substance vapour pressure was determined to be 2.6 Pa (at 50°C) based on a result taken from peer reviewed handbook data.

Reference 2

Endpoint:

vapour pressure

Type of information:

not specified

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Authoritative database

Qualifier:

no guideline followed

Principles of method if other than guideline:

The authoritative database form the Institute for Occupational Safety and Health of the German Social Accident Insurance (GESTIS database) is regarded as reliable literature source and was taken into account in this weight of evidence approach. The GESTIS database reports the vapour pressure to be 2.6 Pa at 50°C.

GLP compliance:

not specified

Type of method:

other: unknown method

Temp.:

50 °C

Vapour pressure:

2.6 Pa

Conclusions:

The test substance vapour pressure was determined to be 2.6 Pa (at 50°C) based on a GESTIS database query.

Reference 3

Endpoint:

vapour pressure

Type of information:

(Q)SAR

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Justification for type of information:

Results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification. Full details are located in the QPRF attached in the field: 'attached background material'.

Qualifier:

no guideline followed

Principles of method if other than guideline:

Results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification. Full details are located in the QPRF attached in the field: 'attached background material'.

GLP compliance:

no

Type of method:

other: QSAR result

Temp.:

25 °C

Vapour pressure:

0.023 Pa

Remarks on result:

other:

Remarks:

Calculated using QSAR (MPBPWIN of EPISuite)

Conclusions:

The vapour pressure of the substance is 0.02253148 Pa (at 25°C) based on the results of QSAR.

Description of key information

A total of two vapour pressure values (both 2.6 Pa at 50°C) are available for this substance based on reliable handbook/secondary source data. This endpoint has also been assessed using QSAR which provides a lower value of 0.02 Pa at 25°C (the lower value is to be expected as the temperature is reduced compared with the handbook/secondary source data). The value of 0.02 Pa at 25°C has been selected as the key value for chemical safety assessment as observed at a more relevant temperature. Overall the weight of evidence assessment is considered reliable and adequate to assess the vapour pressure of the substance.

Key value for chemical safety assessment

Vapour pressure:

0.02 Pa

at the temperature of:

25 °C