Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
boiling point
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 08 May 2017 to 11 May 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Decomposition:
yes
Decomp. temp.:
> 225 °C
Remarks on result:
other: Glass transition point: -65.7°C. No melting between -90°C and the glass transition point.

TGA EXPERIMENT (PRELIMINARY TEST)

From 275°C upwards the weight of the sample decreased significantly: 25% and 70% weight loss at 402°C and 466°C, resp. After the experiment, a dark brown residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test item.

DSC EXPERIMENT 1

During cooling a phase transition was observed between -90°C and -60°C. During heating glass transition was observed between -75°C and -50°C with the inflection point at -65.770°C. An endothermic (reaction/decomposition) peak followed by an exothermic peak was observed between 225°C and 400°C.  After the experiment, a brown residue remained in the sample container.

DSC EXPERIMENT 2

The inflection point of the glass transition was determined to be -65.722°C. No change in appearance was observed after the experiment.

DATA HANDLING

The mean (n=2) inflection point was reported as the glass transition point of the substance: -65.7°C.

 

Conclusions:
The glass transition point of the substance was determined to be -65.7°C. Melting of the substance was not observed between between -90°C and the glass transition point.

Executive summary:

Differential Scanning Calorimetry (DSC) experiments were performed in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200. The glass transition temperature of the substance was determined in duplicate obtaining a mean value of -65.7°C. Melting of the substance was not observed between between -90°C and the glass transition point. Reaction and/or decomposition of the substance started at temperatures above 225°C. Boiling of the substance was not observed below the temperature at which reaction and/or decomposition started.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion