Reaction mass of 3-phenoxybenzyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate and 3-phenoxybenzyl (1R,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate (4:1)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Key result

Water solubility:

5 µg/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.1 other: g/ml

Incubation duration:

2 h

Temp.:

20 °C

Remarks on result:

other: pH not indicated

Details on results:

GC-MS analysis of the 25 mL/h and 12.5 mL/h aqueous fractions

Sample
fraction As Cs(ng/mL) Water Solubility (ug/L)
26 mL/h Al 0 - < 5
25 mUh A2 0 - < 5
25 mUh A3 0 - < 5
26 mL/h A4 0 - < 5
25 mL/h A5 0 - < 5
25 mL/h A6 0 - < 5
25 mUh A7 0 - < 5
26 mL/h A8 0 - <5
26 mUh A9 0 - < 5
26 mL/h A10 0 < 5
12.5 mL/h B1 0 - < 5
12.5 mL/h B2 0 - < 5
12.5 mUh B3 0 - < 5
12.5 mUh B4 0 - <5
12.5 mL/h B5 0 - < 5
12.5 mUh B6 0 - < 5
12.5 mL/h B7 0 - < 5
12.5 mL/h 138 0 - < 5
12.6 mL/h B9 0 - < 5
12.6 mUh B10 0 - < 5

Conclusions:

The test was performed at 20 °C using water analytical grade. The water solubility is found being < 5 µg/L.

Executive summary:

The water solubility of the test material "d-phenothrin pure active substance" has been tested according to the following guidelines: EU A.6 and OECD n. 105.

The test was performed twice using different elution flows: 12.5 mL/hour and 25 mL/hour, collecting the eluate for 2 and 1 hour, respectively.

The pH of distilled water and the pH of each fraction collected were measured to ensure the test article stability in water. Each water fraction was then extracted with 5 mL of hexane and analyzed using the GC operating conditions reported above.

The test was performed at 20 °C using water analytical grade. The water solubility found is < 5 µg/L.

Taking into consideration the functional groups in the d-phenothrin molecular structure, it is reasonable to conclude that a change in the temperature or pH value, give not to a significant variation on the water solubility value.

Description of key information

The water solubility of the test material "d-phenothrin pure active substance" has been tested according to the following guidelines: EU A.6 and OECD n. 105.

The test was performed at 20h°C using water analytical grade and the water solubility found is < 5 µg/L.

Taking into consideration the functional groups in the d-phenothrin molecular structure, it is reasonable to conclude that a change in the temperature or pH value, give not to a significant variation on the water solubility value.

Key value for chemical safety assessment

Water solubility:

5 µg/L

at the temperature of:

20 °C