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EC number: 210-540-0 | CAS number: 618-03-1
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
The half life of hydrolysis of test chemical 2-aminotoluene-4-sulphonic acid ( CAS no. 618 -03 -1) was estimated by using OECD QSAR tool box v3.3 by considering six closest read across chemicals with log Kow as primary descriptor. The half life of test chemical 2-aminotoluene-4-sulphonic acid was estimated to be 297.46 days. On the basis of this half life value it is concluded that test chemical 2-aminotoluene-4-sulphonic acid is not hydrolysable.
Additional information
Hydrolysis:
Predicted data for target chemical 2-aminotoluene-4-sulphonic acid ( CAS no. 618 -03 -1) and experimental study for its structurally similar read across chemical have been conducted and their results are summarized below.
In a predicted data study the half life of hydrolysis of test chemical 2-aminotoluene-4-sulphonic acid ( CAS no. 618 -03 -1) was estimated by using OECD QSAR tool box v3.3 by considering six closest read across chemicals with log Kow as primary descriptor. The half life of test chemical 2-aminotoluene-4-sulphonic acid was estimated to be 297.46 days. On the basis of this half life value it is concluded that test chemical 2-aminotoluene-4-sulphonic acid is not hydrolysable.
Next study was experimental study done from authoritative database (HSDB, 2017) in this study the hydrolysis rate constant of read across chemical 4-aminobenzenesulfonic acid obtained was 2.9X10+9 L/mol-sec L/mol/sec .The half life of hydrolysis obtained at pH 7 was 276 days. Since half life of hydrolysis is more than 10 days so it is concluded that read across chemical 4-aminobenzenesulfonic acid shows negligible hydrolysis that means it is not hydrolysable.
On the basis of both the studies mentioned above it can be concluded that test chemical 2-aminotoluene-4-sulphonic acid (CAS no. 618 -03 -1) is not hydrolysable.
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