Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08.04.-07.05.2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
(1r,4r)-4-(2,3-difluoro-4-propoxyphenyl)-4'-propyl-1,1'-bi(cyclohexane)
EC Number:
610-336-5
Cas Number:
473257-14-6
Molecular formula:
C24H36F2O
IUPAC Name:
(1r,4r)-4-(2,3-difluoro-4-propoxyphenyl)-4'-propyl-1,1'-bi(cyclohexane)

Results and discussion

Water solubility
Key result
Water solubility:
< 0.09 mg/L
Conc. based on:
test mat. (dissolved fraction)
Temp.:
20 °C
pH:
5.5

Applicant's summary and conclusion

Executive summary:

The water solubility of the test substance was < 0.09 mg/L.