Registration Dossier
Registration Dossier
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EC number: 211-317-0 | CAS number: 638-07-3
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
A study was carried out according to OECD Guideline 111 (hydrolysis in function of pH). In the course of the preliminary test, the test item was found to be hydrolytically stable at
50°C at pH 4 (<10% hydrolysis after 5 days), whereas full hydrolysis (100%) was noted at pH 7 and 9 at 50°C. Therefore, further testing was necessary at pH 7 at 40°C and at pH 9 at 30°C and 40°C. At pH 7, the half-life times were 9.43 h at 40°C and 2.05 h at 50°C; at pH 9, t1/2 were 1.04 h at 30°C and 0.98 h at 40°C.
In conclusion, the extrapolated half-life times were as follows:
- pH 4 at 25°C: > one year (> 8760 hours)
- pH 7 at 25°C: 4.9 days (118 hours)
- pH 9 at 30°C: 1.04 hours
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 118 h
- at the temperature of:
- 25 °C
Additional information
Source: non-GLP-report
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