Registration Dossier

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Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information

Experimental data on reproductive toxicity of TBBP are not available. VegaNIC software predicted reliable data about “Estrogen Receptor-mediated effect”.

A large number of environmental chemicals, known as endocrine-disrupting chemicals, are suspected of disrupting endocrine functions by mimicking or antagonizing natural hormones, and such chemicals may pose a serious threat to the health of humans and wildlife. They are thought to act through a variety of mechanisms, mainly estrogen-receptor-mediated mechanisms of toxicity.

Prediction is: Possible NON-active.

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available

Justification for classification or non-classification

Considering the prediction for the substance as "Possible NON-active" for the "Estrogen Receptor-mediated effect”; data are judged as inconclusive for the classification.

Additional information

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