Registration Dossier
Registration Dossier
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EC number: 701-372-3 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
CAS 27614 -71 -7 is with high probability acutely not harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- > 100 mg/L
Additional information
In order to assess the acute toxicity to fish, experimental data are available for the substance itself and for the two structural similar substances CAS 1328-53-6 and CAS 147 -14 -8. Test concentrations were not analytically verified in these static toxicity tests. The key study conducted according to OECD 203 was performed with the substance (96-h LC50 > 100 mg/L; nominal, Clariant GmbH, 2000).
There are further experimental data on the analogous substances which support the key result. In a limit study according to OECD TG 203 with Polychloro copper phthalocyanine (CAS 1328-53-6) no mortality of fish was observed at the end of the test, therefore the 96-h LC50 was determined to be higher than 100 mg/L (nominal, Colour Chem. Lim., 2000). Tween-80 was used as a vehicle. The concentration of the vehicle was 1 g/L. Additionally, two non-GLP tests conducted according to EPA-660/3-75-009 were performed with a source substance CAS 1328-53-6. The 96-h LC50 was determined to be 752 mg/l for Lepomis macrochirus as a test organism (nominal, Sun Chem Corp., 1978). Whereas in a second test conducted with Oncorhynchus mykiss as a test organism the 96-h LC50 was determined to be 356 mg/L (nominal, Sun Chem Corp, 1978). No vehicle was used in both studies. In support of this result, the 96-h LC50 of CAS 147-14-8 was determined in an OECD 203 guideline study with Danio rerio to be higher than 100 mg/L (nominal, BASF AG, 2004).
In conclusion it can be considered, that based on the available experimental data for the substance along with the supporting read-across data for the structurally similar substances, it can be concluded that CAS 27614 -71 -7 is with high probability acutely not harmful to fish.
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