Registration Dossier
Registration Dossier
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EC number: 203-597-8 | CAS number: 108-59-8
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449/EEC, C.2 "Acute toxicity for Daphnia"
- GLP compliance:
- yes
Test material
- Reference substance name:
- Dimethyl malonate
- EC Number:
- 203-597-8
- EC Name:
- Dimethyl malonate
- Cas Number:
- 108-59-8
- Molecular formula:
- C5H8O4
- IUPAC Name:
- dimethyl malonate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Strain: Daphnia magna Straus IRCHA
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Ca/Mg ratio: 4 : 1
- Test temperature:
- 20 +- 2°C
- Dissolved oxygen:
- 7.7-8.4 mg/L
- Nominal and measured concentrations:
- 2g/L
- Details on test conditions:
- CaCl2×2H2O 294mg/L
MgSO4×7H2O 123mg/L
NaHCO3 63mg/L
KCl 5.5 mg/L
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
Any other information on results incl. tables
concentrations:
results(immobilization)(24h):
concentration(mg/L) |
immobilized daphnias(%) |
0.9 |
30 |
1.9 |
100 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
