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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental dates: 25 May 2017 to 06 June 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
as amended by Commission Regulation (EC) 761/2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Inspected on 05/07/2016 / Signed on 28/10/2016
Type of method:
gas saturation method
Key result
Temp.:
25 °C
Vapour pressure:
1.34 Pa

Results of the vapor pressure determinations

Saturator

Column.

Temperature (°C)

Volume* V (mL)

Mass of test item in Trap 1 (µg)

Mass of test item in Trap 2 (µg)

Total mass of

test item (µg)

Vapor pressure

(Pa)

Average Vapor pressure [Pa] (Std Dev)

A

15

46484

1870

0

1870

0.502

0.499 (0.005)

B

61675

2440

0

2440

0.493

C

77929

3130

0

3130

0.501

A

25

36674

3740

0

3740

1.31

1.31 (0.004)

B

48299

4900

0

4900

1.31

C

61483

6270

0

6270

1.31

A

35

10356

2710

0

2710

3.48

3.47 (0.03)

B

13741

3550

0

3550

3.44

C

17362

4550

0

4550

3.49

  * corrected volume at test temperature

                                     

The regression parameters of the Vapour Pressure curve ln(VP) = f (1/T) are:

slope = -8613

intercept = 29.18

r2= 0.999

Conclusions:
Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, gas saturation method. Determinations were conducted at 15, 25 and 35°C, with three flow rates per temperature. Mass of evaporated test item was quantified by GC. Vapor pressure at 25 °C was interpolated from the regression.

The vapor pressure of the test item has been determined to be 1.34 Pa at 25 °C.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:
1.34 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result is retained as key data for purpose of CSA.