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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 11 to 26 January 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Principles of method if other than guideline:
not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
inspected on 13 and 14 October 2014 / signed on 08 April 2015
Type of method:
method according to Siwoloboff
Key result
Boiling pt.:
199.3 °C
Atm. press.:
101.325 kPa
Decomposition:
no
Remarks on result:
other: 199.3 ± 0.6 °C (472.4 ± 0.6 K)

Observations and measured values are presented in the following table.

Table 1-Results

Determination

Boiling Point

Atmospheric Pressure

First determination

198.6 °C (471.8 K)

100898 Pa

Second determination

199.4 °C (472.6 K)

100664 Pa

Table 2.-Observations

Observation

First

determination

Second

determination

Boiling chain,

heating switched off

211.8 °C

214.5 °C

After cooling down

The tinge of yellow was more intense

Corrected values following Sidney-Young: to calculate the boiling temperature at standard pressure (101325 kPa)

Table 3.-Corrected values to the standard presure 101.325kPa

 

Boiling point

Pressure in Pa

Corrected Boling point

First determination

198.6 °C (471.8 K)

100898 Pa

198.8 °C (472.0 K)

Second determination

199.4 °C (472.6 K)

100664 Pa

199.7 °C (472.9 K)

Mean

 

 

199.3 °C (472.4 K)

Mean ± standard deviation (after correction following Sydney Young) = 199.3 ± 0.6 °C (472.4 ± 0.6 K) at standard pressure (101.325 kPa).

Conclusions:
The initial boiling temperature of the test item has been determined to be ca 199.3 ± 0.6 °C, corrected to standard pressure (101.325 kPa).
Executive summary:

The initial boiling point of the test item was measured under GLP according to OECD 103 / EU A2 guideline, by Siwoloboff.

The test item was filled into a sample tube.

The sample tube was then set into the aluminium block at 185.0 °C (first determination) and at 185.6 °C (second determination).

For the increase of the temperature, a temperature gradient of 1 °C /min was maintained. When bubbles rose constantly on the capillary, heating was turned down, and, cooling slowly. The moment at which the chain of bubbles broke was recorded (with its atmospheric pressure) as boiling point. The determination was performed in duplicate with fresh samples.

The test item was unchanged after cooling down for each determination.

Description of key information

The initial boiling temperature of the test item has been determined to be ca 199.3 ± 0.6 °C, corrected to standard pressure (101.325 kPa).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
199.3 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study.

The initial boiling point of the test substance was measured by Siwoloboff method..The test item was filled into a sample tube.

The sample tube was then set into the aluminium block at 185.0 °C (first determination) and at 185.6 °C (second determination).

For the increase of the temperature, a temperature gradient of 1 °C /min was maintained. When bubbles rose constantly on the capillary, heating was turned down, and, cooling slowly. The moment at which the chain of bubbles broke was recorded (with its atmospheric pressure) as boiling point. The determination was performed in duplicate.

The test item is unchanged after cooling down for each determination.