Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 231-154-9 | CAS number: 7440-45-1
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Type of information:
- experimental study
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 988
Materials and methods
Test material
- Reference substance name:
- Cerium
- EC Number:
- 231-154-9
- EC Name:
- Cerium
- Cas Number:
- 7440-45-1
- Molecular formula:
- Ce
- IUPAC Name:
- cerium(3+)
Constituent 1
Results and discussion
In vivo
- Irritant / corrosive response data:
- REACH states in Annex VII, "8.1. Skin irritation or skin corrosion / in vitro study" that the in vitro study for skin corrosion can be waived if the substance is flammable in air at room temperature. However, an assessment of the available human and animal data as well as an assessment of the acid or alkaline reserve shall be done.
In this case, the acid or alkaline reserve study cannot be performed due to the solubility properties of cerium. Solids shall be brough into a 10% solution (i.e. 100.000 mg/L) which is about eigth orders of magnitude higher than the solubility of cerium itself (2,7* 10E-3 mg/L).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
