Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The partition coefficient could not be determined for lithium salts of fatty acids predominantly C24-C28 (saturated) as the tests are not technically feasible on this substance.

Key value for chemical safety assessment

Additional information

No determination was carried out using the shake-flask method or HPLC estimation method as lithium salts of fatty acids predominantly C24 - C28 (saturated) was insufficiently soluble in n-octanol and water which prevented the use of the shake-flask method and the HPLC method is not suitable for salts of organic acids.

The partition coefficients were estimated by QSAR model, KOWWIN (KOWWIN v1.67 in EPISuite v4.11, US EPA 2009b), for the main constituents of lithium salt of fatty acids predominantly C24 - C28 (saturated), with Log Kow values for lithium tetracosanoate of 7.64, for lithium hexacosanoate of 8.63 and lithium octacosanoate of 9.61.

The lithium salts of fatty acids predominantly C24 - C28 (saturated) is not synthesized as the “pure” compound and does not exist except in the presence of the oil matrix. High temperature stability indicates that the grease thickener structure is robust and resistant to diffusion out of the oil. Dissolution of grease thickener from grease into water is very unlikely as the thickener is poorly water soluble and the thickeners are embedded in the hydrophobic grease matrix and thus less likely to leach out. Thus, the partition coefficient of the substance is not expected to be relevant. Since the predicted log Kow values for the substance are greater than 6, the thickener is expected to reside within the grease base oil matrix and is not expected to favourably partition to water. Hence the substance is expected to have significantly limited bioavailability.