Registration Dossier
Registration Dossier
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EC number: 206-017-1 | CAS number: 288-13-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
There is no study available for pyrazole concerning skin sensitization.
However, read-across to 1,4 -dimethylpyrazole has been performed. In a GLP-compliant guideline study (according to OECD TG 406; BASF, 1995), 1,4 -dimethylpyrazole showed no skin sensitizing properties. Moreover, pyrazole does not show a sensitizing alert (protein binding) in QSAR modeling (OECD Toolbox v.1.0). Therefore, no sensitzing potential is expected.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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