Registration Dossier
Registration Dossier
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EC number: 206-017-1 | CAS number: 288-13-1
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: guideline study (no GLP)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- ISO 7827 (Evaluation in an Aqueous Medium of the "Ultimate" Aerobic Biodegradability of Organic Compounds - Method by Analysis of Dissolved Organic Carbon (DOC))
- GLP compliance:
- no
Test material
- Reference substance name:
- Pyrazole
- EC Number:
- 206-017-1
- EC Name:
- Pyrazole
- Cas Number:
- 288-13-1
- Molecular formula:
- C3H4N2
- IUPAC Name:
- 1H-pyrazole
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Sewage from wastewater treatment plant Edenkoben, sampling date: 1989- 11-14.
- Pre-treatment: none
- Amount of inoculum: 0.5 mL sewage/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- ca. 19 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST SYSTEM
- Number of culture flasks/concentration: 2
- Test performed in open system: yes
SAMPLING
- Sampling frequency: every 2-7 days for at least 28 days
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes
- Toxicity control: yes
- Inhibition of the inoculum: yes
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- < 15
- Sampling time:
- 28 d
- Details on results:
- < 15% after 0, 1, 3, 7, 14, 21, 28 d
BOD5 / COD results
- Results with reference substance:
- ca. 10% after 1 day
> 95% after 3 and 7 days
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: poorly biodegradable
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