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EC number: 218-737-3 | CAS number: 2222-33-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from J-CHECK authoritative database
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Principles of method if other than guideline:
- These tests are conducted based on OECD-GLP standard and OECD test guidelines.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 1H-dibenzo[a,d][7]annulen-1-one
- Molecular formula (if other than submission substance): C15H10O
- Molecular weight (if other than submission substance): 206.243 g/mol
- Smiles notation (if other than submission substance): c12c(ccc3c(c1=O)cccc3)cccc2
- InChI: 1S/C15H10O/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-10H
- Substance type: Organic
- Physical state: Solid - Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Fish
- Details on test organisms:
- No data available
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Hardness:
- No data available
- Test temperature:
- No data available
- pH:
- No data available
- Dissolved oxygen:
- No data available
- Salinity:
- No data available
- Nominal and measured concentrations:
- 2.5 mg/L
- Details on test conditions:
- No data available
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 2.5 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Short term toxicity to fish study was carried out for 96 hrs. according to OECD Guideline 203 (Fish, Acute Toxicity Test). For chemical 1H-dibenzo[a,d][7]annulen-1-one (Cas no. 2222-33-5), based on effect on mortality of the fish, the 96 hr LC50 value was determined to be >2.5 mg/l.
- Executive summary:
Short term toxicity to fish study was carried out for 96 hrs. The study was performed according to OECD Guideline 203 (Fish, Acute Toxicity Test). The study was based on the effects of the test compound 1H-dibenzo[a,d][7]annulen-1-one on fish in fresh water system. Based on effect on mortality of the test organism fish, the 96 hr LC50 value was determined to be >2.5 mg/l. Thus, based on the LC50 value, it can be concluded that the substance 1H-dibenzo[a,d][7]annulen-1-one can be considered as toxic to fish and thus can be classified as aquatic acute category 2 as per the CLP classification criteria.
Reference
Description of key information
Short term toxicity to fish study was carried out for 96 hrs. according to OECD Guideline 203 (Fish, Acute Toxicity Test). For the test chemical, 1H-dibenzo[a,d][7]annulen-1-one (Cas no. 2222-33-5), the 96 hr LC50 value was determined to be >2.5 mg/l based on mortality effects observed in fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.5 mg/L
Additional information
Short term toxicity to fish study was carried out for 96 hrs. The study was performed according to OECD Guideline 203 (Fish, Acute Toxicity Test). The study was based on the effects of the test compound 1H-dibenzo[a,d][7]annulen-1-one on fish in fresh water system. Based on effect on mortality of the test organism fish, the 96 hr LC50 value was determined to be >2.5 mg/l. Thus, based on the LC50 value, it can be concluded that the substance 1H-dibenzo[a,d][7]annulen-1-one can be considered as toxic to fish and thus can be classified as aquatic acute category 2 as per the CLP classification criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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