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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
yes
Remarks:
Scrrening
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl pyruvate
EC Number:
209-987-4
EC Name:
Methyl pyruvate
Cas Number:
600-22-6
Molecular formula:
C4H6O3
IUPAC Name:
methyl 2-oxopropanoate
Test material form:
liquid
Details on test material:
CAS: 600-22-6
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Duration of testopen allclose all
Duration:
51 h
pH:
4
Temp.:
50 °C
Initial conc. measured:
950 mg/L
Duration:
51 h
pH:
7
Temp.:
23 °C
Initial conc. measured:
910 mg/L
Duration:
51 h
pH:
9
Temp.:
23 °C
Initial conc. measured:
980 mg/L

Results and discussion

Transformation products:
not specified
Dissipation DT50 of parent compoundopen allclose all
Key result
pH:
7
Temp.:
23 °C
DT50:
4.1 h
Type:
(pseudo-)first order (= half-life)
pH:
4
Temp.:
50 °C
DT50:
9.2 h
Type:
(pseudo-)first order (= half-life)
pH:
9
Temp.:
23 °C
DT50:
ca. 0.5 min
Type:
(pseudo-)first order (= half-life)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes