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EC number: 212-728-8 | CAS number: 860-22-0
In a vitro biometabolism study, Wistar male rats caecum extract were treated with Indigo Carmine in the concentration of 1 mg and comparative degradation patternwas estimated at different time interval and expressed as degradation index 50 (DI 50) value i.e. the time period required to degrade 50 % of the original Indigo Carmine concentarion present in the incubation system. 4 fluorescent metabolite spots were detected with maximum degradation of 72.6 % after 6 and 18 hours. Indigo Carmine showed faster degradation with DI 50 value of 54 min.Therefore, On the basis of given result Indigo Carmine expected to have Low bio-accumulation potential based on study results.
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