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Registration Dossier
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EC number: 426-200-1 | CAS number: 172015-79-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annex V
- GLP compliance:
- yes
- Limit test:
- yes
Test animals
- Species:
- other: Rat (Wistar)
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- other: Substance moistened with deionised water.
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: There were no significant signs of systemic toxicity.
- Gross pathology:
- Effects on organs:
There were no toxiclogically significant pathology
abnormalities observed. - Other findings:
- Signs of toxicity (local):
Slight to moderate oedema was seen in most animals and
scabbing was seen in two animals. All signs of irritation
had completely resoved by day 7.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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