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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Emergency measure - Inhalation: Remove to fresh air.  Symptomatic treatment.  Obtain

immediate medical attention.

Emergency measure - Eyes: Wash thoroughly with water and continue for at least 15 minutes.  Seek medical attention.

Emergency measure - Skin: Remove contaminated clothing and launder before reuse.

Thoroughly wash all affected areas with soap and water. Seek medical attention.

Emergency measure - Ingestion: Seek immediate medical attention.

Fire-fighting measures

Recommended extinguishing agent: Water, foam, powder or carbon dioxide.

Product arising from burning: Noxious fumes (eg carbon and nitrogen oxides and chlorine

containing compounds).

Product determined by test: N

Protective equipment: Full protective clothing and a self-contained breathing apparatus must be worn.

Accidental release measures

Emergency measures in case of spillage: Ensure suitable protective clothing during removal of


Damp down and sweep up into a container for disposal.  Wash the spillage area with water.

Disposal should be in accordance with local, state or national legislation.

Handling and storage

Handling: The substance should be stored, handled and used under

conditions of good industrial hygiene and in conformity with

any local regulations in order to avoid exposure by skin and eye contact, ingestion and inhalation.

Storage: Keep container tightly closed in a cool dry place.

Packaging of the substance and or preparation: Polythene lined fibre board kegs.

Transport information

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Marine transport (UN RTDG/IMDG)

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Air transport (UN RTDG/ICAO/IATA)

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Special provisions / remarks
Transport code: None
Transport: Avoid crushing the containers.
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Exposure controls / personal protection

Occupational Hygiene Air

Monitoring Methods

An occupational/industrial hygiene monitoring method has been developed for this material.  For

advice on suitable monitoring methods, seek guidance from a qualified environment, health and

safety professional.


Exposure Controls

This material has been assigned to GlaxoSmithKline Occupational Hazard Category 3 with a

hygiene guide of 10 - <100 mcg/m3. An Exposure Control Approach (ECA) is established for

operations involving this material based upon the OEL/Occupational Hazard Category and the

outcome of a site- or operation-specific risk assessment. Refer to the Exposure Control Matrix for

more information about how ECA's are assigned and how to interpret them.


Open handling is not recommended. Consider segregating operations, use of enclosures and

sealed transfer systems.


Local exhaust ventilation (LEV) should be used in conjunction with other control measures as a

means of removing material incidentally released.


Entry to the working area should be controlled. Doors with interlocks may be needed for materials

airlocks and locker rooms. Only equipment and supplies necessary for job activities should be

taken into working area.


Eye Protection

Wear approved cover goggles if eye contact is possible. In addition, a face shield is



The selection of gloves for a specific activity must be based on the material's properties and on

possible permeation and degradation that may occur under the circumstances of use. Glove

selection must take into account any solvents and other hazards present. Potential allergic

reactions can occur with certain glove materials (e.g. Latex) and therefore these should be

avoided. Care must be exercised if insufficient data are available and further guidance should be

sought from your local EHS department.


If respiratory protective equipment (RPE) is used, the type of RPE will depend upon air

concentrations present, required protection factor as well as hazards, physical properties and

warning properties of substances present. RPE should provide full face protection. Follow local

regulations for respirator use in the workplace.

Other Equipment or


Consider control procedures for maintenance, cleaning and emergencies. Eye wash and shower

stations should be available. Wear appropriate clothing to avoid skin contact.

Stability and reactivity

Danger other than fire: None reported.

Chemical reaction with water: None reported.

Dust explosion: There is a potential for dust explosion of this organic

powder when it becomes airbourne.  However, appropriate

handling and storage procedures are used to minimise the risk of electrostatic discharge.

Dust explosion determined by test: N

Disposal considerations

Industry - Possibility of recovery/recycling: Handling of the substance will be by trained operators, and

will be kept to a minimum.

Discharge to the environment will be minimal.  Recovery from minor spillages or accidental discharge is not economically

or technically feasible, and such waste material wiil be

disposed of by incineration.  In principle, it may be possible to recover larger spillages of uncontaminated

material for subsequent use.

Industry - Possibility of neutralisation: The notification tests have shown that the substance is

toxic, an eye irritant, a  skin sensitiser and dangerous for

the environment.

No chemical treatment is practicable to neutralise the

hazardous health properties.

The potential dust storage hazard will be minimised by

appropriate handling and storage.

No chemical treatment is practicable to neutralise the

hazardous environmental properties.

Industry - Possibility of destruction: controlled discharge: Contaminated containers or spillages of solutions mixed with

inert material (eg. sand or soil) should be disposed of by

incineration in accordance with local regulations.

Industry - Possibility of destruction - incineration: The substance can be disposed of by incineration by burning

under controlled conditions at a licensed waste treatment

processor in accordance with local regulations.  Stack gases should be scrubbed, because noxious fumes (eg. carbon and

nitrogen oxides and chlorine-containing compounds) could be


Industry - Possibility of destruction - water purification: The substance will not normally be discharged directly to the sewage system or the aqueous environment.

Public at large - Possibility of recovery/recycling: Not applicable

Public at large - Possibility of neutralisation: Not applicable

Public at large - Possibility of destruction: controlled discharge: Not applicable

Public at large - Possibility of destruction - incineration: Not applicable

Public at large - Possibility of destruction - water purification: Not applicable

Public at large - Possibility of destruction - others: Not applicable