Registration Dossier
Registration Dossier
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EC number: 242-060-2 | CAS number: 18172-67-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity to microorganisms of (-)-beta-pinene was determined in a read-across approach.
A respiration inhibition study was performed to assess the effect of delta-3-carene on STP microorganisms according to OECD guideline No 209.
The 3h-EC50 of delta-3-carene for inhibition of respiration of activated sludge is 326 mg/L.
The 3h-EC10 of delta-3-carene for inhibition of respiration of activated sludge is 38 mg/L.
Therefore, delta-3-carene is considered harmful to activated sludge.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 326 mg/L
- EC10 or NOEC for microorganisms:
- 38 mg/L
Additional information
The toxicity to microorganisms of (-)-beta-pinene was determined in a read-across approach.
Key study conducted on delta-3 -carene according to OECD 209 Guideline under GLP without deviation.
Delta-3-carene was tested at nominal concentrations of 0 (control), 17.3, 34.6, 69.1, 138.2, 276.5, 553 mg/L and the inoculum (microbial source) was activated sludge of a predominantly domestic sewage.
The validity criteria were fulfilled and the observed 3h-EC50 and 3h-EC10 values can be used for chemical safety assessment.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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