Registration Dossier
Registration Dossier
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EC number: 605-104-5 | CAS number: 157577-99-6
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 24, 2012
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: non GLP study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Principles of method if other than guideline:
- The sample was dispersed, stirred and ultrasonicated prior the analytical characterisation by light scattering.
- GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Percentile:
- D50
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D10
- Mean:
- ca. 24.414 µm
- St. dev.:
- 2
- Percentile:
- D50
- Mean:
- ca. 54.147 µm
- St. dev.:
- 5
- Percentile:
- D90
- Mean:
- ca. 101.8 µm
- St. dev.:
- 5
- Conclusions:
- Acid Black 234 particle size distribution was measured by light scattering and the results are D10=24.4 um, D50= 54.15 um and D90= 101.80 um.
- Executive summary:
Acid Black 234 particle size distribution was measured by light scattering and the results are D10=24.4 um, D50= 54.15 um and D90= 101.80 um.
Reference
Description of key information
D10=24.4 um, D50= 54.15 um and D90= 101.80 um.
Additional information
Acid Black 234 particle size distribution was measured by light scattering and the results are D10=24.4 um, D50= 54.15 um and D90= 101.80 um.
The value is considered within the inhalable fraction, but not in the thoracic or respirable fraction. Since the usual form present on the market is liquid and the solid form is always treated with antidusting materials, this value is too much conservative in respect to the real form present in the market, therefore it is not indicative of the need to test the respiratory toxicity as preferred exposure route
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