Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 931-038-4 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (n/i-C13 -C15 –aldehydes; OECD 310; toxicity control): 23.6 mg/L (Harlan, 2011)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 23.6 mg/L
Additional information
n/i-C13 -C15 –aldehydes (23.6 mg/L), a mixture of n/iso C13 and C15 aldehydes, was tested for ready biodegradation in an OECD TG 310 assay under GLP conditions (Harlan, 2011) . In the toxicity control for inoculum toxicity, the biodegradation of the reference item 1-octanol (25.4 mg/L in the test) was not inhibited by the n/i-C13 -C15 –aldehydes at 23.6 mg/L, i.e. there was no toxicity to microorganisms at this concentration. According to the ECHA Guidance Document on Information Requirements and Chemical Safety Assessment, parts R.7b and R.10, this concentration can be considered as a NOEC. Consequently, the NOEC for microorganism toxicity equals 23.6 mg/L, and no further tests on STP microorganism toxicity have to be conducted.
This result is supported by an earlier (not reliable) study on ready biodegradability of n/i-C13 -C15 –aldehydes according to OECD TG 301F (Hoechst, 1995). In the toxicity control (n/i-C13 -C15 –aldehydes at nominal 1002 mg/L), the biodegradation of the reference substance sodium benzoate was 64% within 14 days. Thus, n/i-C13 -C15 –aldehydes were not toxic to microorganisms and, according to these data, 1002 mg/L would correspond to the NOEC for STP microorganisms toxicity.
For the assessment of the PNECstp, the NOEC of the OECD 310 study (Harlan, 2011) was used since this value is closer to the water solubility limit of n/i-C13 -C15 –aldehydes (2 mg/L @ 20 °C; OXEA, 2009).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
