Registration Dossier
Registration Dossier
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EC number: 221-221-0 | CAS number: 3033-77-0
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was well-documented and met generally accepted scientific principles. However, it was not conducted in compliance with GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
- Principles of method if other than guideline:
- Method: other: abiotic hydrolysis at pH 7.8 and 12 °C
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,3-epoxypropyltrimethylammonium chloride
- EC Number:
- 221-221-0
- EC Name:
- 2,3-epoxypropyltrimethylammonium chloride
- Cas Number:
- 3033-77-0
- Molecular formula:
- C6H14NO.Cl
- IUPAC Name:
- N,N,N-trimethyl(oxiran-2-yl)methanaminium chloride
Constituent 1
Results and discussion
- Transformation products:
- yes
Total recovery of test substance (in %)
- % Recovery:
- 17.7 - 84.2
- pH:
- 7.8
- Duration:
- 49 d
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 7.8
- Temp.:
- 12 °C
- DT50:
- 177 d
- Details on results:
- Total recovery derived from following IUCLID4 degradation at pH 7.8Degradation (in %): ca. 15.8 ... 17.7 after 49day(s)
Any other information on results incl. tables
A linear ln c(EPTAC) versus time curve was obtained
indicating a pseudo first order reaction.
The test was performend in dublicate and EPTAC half-lives of
approximately 170 days (4081 h) and 185 days (4432 h) were
received in test series. The combined degradation rate was
177 days (4265.5 h). The average constant k(obs) was 1.7 x
10 E-4 [h-1].
It was observed from both test series that as the
concentration of EPTAC decreased, the concentration of bot
CHPTAC and DIOL increased.
In the test series A there were two test points in which pH
exceeded the target ph 7.8 +-0.1. This led to the increase
of EPTAC concentration in one of the test point times and
also decrease of CHPTAC was observed. In the test series B
there were one test point where pH exceeded slightly the
target pH but no increase of the concentration of EPTAC was
observed.
Applicant's summary and conclusion
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