Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Acute/short term exposure
DNEL related information

Workers - Hazard via dermal route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Acute/short term exposure
Most sensitive endpoint:
skin irritation/corrosion

Workers - Hazard for the eyes

Additional information - workers

The most prominent acute effect of the test material is acute irritation/corrosion, as indicated by the in vitro test results on human skin. Consequently, there is no need to conduct other mandatory tests such as acute oral, acute eye and sensitisation tests.

On the other hand, Ames test results on S. typhimurium and E.coli strains have shown that Inositol phosphates is not mutagenic under test conditions.

Based on the above results, the test material satisfies the criteria for classification as C, R34 (corrosive, causes severe burns) according to the DSD and 'Skin corrosive category 1A' according to GHS.

General Population - Hazard via inhalation route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Acute/short term exposure
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Acute/short term exposure
Most sensitive endpoint:
skin irritation/corrosion

General Population - Hazard via oral route

Systemic effects

Acute/short term exposure
DNEL related information

General Population - Hazard for the eyes

Additional information - General Population

The most prominent acute effect of the test material is acute irritation/corrosion, as indicated by the in vitro test results on human skin. Consequently, there is no need to conduct other mandatory tests such as acute oral, acute eye and sensitisation tests.

On the other hand, Ames test results on S. typhimurium and E.coli strains have shown that Inositol phosphates is not mutagenic under test conditions.

Based on the above results, the test material satisfies the criteria for classification as C, R34 (corrosive, causes severe burns) according to the DSD and 'Skin corrosive category 1A' according to GHS.