Registration Dossier
Registration Dossier
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EC number: 619-738-5 | CAS number: 87305-03-1
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8 May 2001 to 15 May 2001
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one
- Cas Number:
- 87305-03-1
- Molecular formula:
- C8H9Br3O2
- IUPAC Name:
- (1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- occlusive
- Vehicle:
- water
- Controls:
- yes, concurrent vehicle
- Duration of treatment / exposure:
- 4 h
- Observation period:
- 1, 24, 48, 72 h
- Number of animals:
- 3
Results and discussion
In vivo
Results
- Irritation parameter:
- erythema score
- Basis:
- animal #3
- Time point:
- other: 4 h
- Score:
- 0
- Remarks on result:
- other: No evidence of skin irritation was noted during the study.
Applicant's summary and conclusion
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