Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 210-483-1 | CAS number: 616-45-5
Endpoint summary
Administrative data
Description of key information
Additional information
Toxicity to soil organisms:
2-Pyrrolidone is not supposed to be directly applied to soil. Furthermore, the test substance is readily biodegradable and hence, in case of indirect exposure of soil, 2-pyrrolidone is expected to rapidly degrade. Therefore soil is not expected to be a compartment of concern. The risk to soil organisms is negligible. Hence the soil toxicity endpoints can be waived.
Toxicity to birds:
In Annex X of the Regulation (EC) No 1907/2006, it is suggested, that in case of long term toxicity testing to birds "any need for testing should be carefully considered taking into account the large mammalian dataset that is usually available at this tonnage level." Furthermore, ECHA (2008) states in the "Guidance on information requirements and chemical safety assessment Chapter R.7c" that "given that mammalian toxicity is considered in detail for human health protection, the need for additional data for birds must be considered very carefully – new tests are a last resort in the data collection process." As the substance is not bioaccumulative and because of reasons of animal welfare, no study on toxicity in birds is performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
