Registration Dossier
Registration Dossier
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EC number: 200-860-9 | CAS number: 75-31-0
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- other: expert statement
- Adequacy of study:
- supporting study
- Principles of method if other than guideline:
- The stability of the test substance in organic solvents under normal ambient conditions was evaluated.
Structurally related chemicals often show similar behaviour according to their chemical structure. The evaluation is restricted to pure "common" organic solvents (Commodities), appropriate ambient conditions and evaluation of hydrolysis, photolysis and of oxidation. - GLP compliance:
- no
- Conclusions:
- The substance is stable in common organic solvents; solvents containing a carbonyl moiety may lead to imines formation with primary amines.
- Executive summary:
This assessment is based on text-book chemical knowledge and practical handling experience.
Primary aliphatic alkyl amines are known to react with carbonyl groups under formation of imines. With respect to common organic solvents not bearing the carbonyl moiety, aliphatic alkyl amines
are known to be stable.
Overall result:
The substance is stable in common organic solvents; solvents containing a carbonyl moiety may lead to imines formation with primary amines.
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the stability of the substance is not considered to be critical
Referenceopen allclose all
Description of key information
Stable in common organic solvents
Additional information
The stability of the submission substance in organic solvents is not considered to be critical (no testing required): based on text-book chemical knowledge and practical handling experience, the substance is stable in common organic solvents; solvents containing a carbonyl moiety may lead to imines formation with primary amines.
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