Registration Dossier
Registration Dossier
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EC number: 203-404-7 | CAS number: 106-50-3
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- repeated dose toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 958
Materials and methods
- Principles of method if other than guideline:
- Guinea pigs were exposed to the test substance via inhalation (duration not specified).
- GLP compliance:
- no
Test material
- Details on test material:
- - Purity: Not reported
Constituent 1
Test animals
- Species:
- guinea pig
Administration / exposure
- Route of administration:
- inhalation
Results and discussion
Effect levels
- Basis for effect level:
- other: Repeated inhalation of the test substance in sensitised guinea pigs induced attacks of dyspnoea. The attacks were caused mainly by toxic irritation of the respiratory system.
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specified (migrated information)
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Repeated inhalation of the test substance in sensitised guinea pigs induced attacks of dyspnoea. The attacks were caused mainly by toxic irritation of the respiratory system.
- Executive summary:
Guinea pigs were exposed to the test substance via inhalation (duration not specified). Repeated inhalation of the test substance in sensitised guinea pigs induced attacks of dyspnoea. The attacks were caused mainly by toxic irritation of the respiratory system.
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