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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-09-30
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Remarks:
Test procedure in accordance with national standard methods (ASTM) without GLP.
Qualifier:
according to
Guideline:
other: ASTM E 1148
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
< 1 mg/L
Temp.:
23 °C
pH:
5.5
Remarks on result:
other: detection limit 1 mg/L

Measurement

(triple determination)

Results:Not Detected / Not Detected / Not Detected

Mean Concentration in Water:<1.0 mg/L

Standard Deviation for These Data:none

Conclusions:
A water solubility value of <1 mg/L at 23 °C and pH 5.5 was determined for the substance using a relevant test method. The result is considered to be reliable.
Executive summary:

Docosan-1 -ol was determined according ASTM E 1148. The water solubility was under the detection limit (1 mg/L).

Description of key information

The water solubility of a commercial sample of docosan-1-ol is <1 mg/L at 23°C and pH 5.5. An estimated water solubility of ca. 0.001 mg/L (Fisk et al., 2010), using a predictive method based on log Kow and validated based on trends across the category.

Key value for chemical safety assessment

Water solubility:
0.001 mg/L
at the temperature of:
20 °C

Additional information

A water solubility value of <1 mg/L at 23°C and pH 5.5 was determined for the substance with the use of a flask method in accordance with ASTM E 1148. The result is considered to be reliable.

It is supported by an estimated water solubility of ca. 0.001 mg/L (Fisk et al., 2010), using a predictive method based on log Kow.

The predicted result is used in exposure modelling.

Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:

As chain length increases, water solubility decreases, because the free energy required for a molecule to dissolve becomes less favourable for larger molecules.