Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 204-464-7 | CAS number: 121-32-4
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
According to the attached Weight of evidence, a worst-case long-term NOEC/EC10 of 1.18 mg/L for fish is considered as the key value for the purposes of environmental classification and quantitative risk assessment.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- NOEC
- Effect concentration:
- 1.18 mg/L
Additional information
Annex XI, section 1.2 (weight of evidence) states that when a WoE provides adequate information for risk assesment (CSA) and hazard assessment (classification), testing on vertebrates shall be omitted. Please find our WoE in the attached pdf document which provides adequate information for both CSA and hazard classification for the environment. According to annex XI, testing on vertebrate shall be omitted. In addition, since a WoE is available, testing on vertebrates does not represent the last resort. Therefore, according to article 25 of REACH, no study should be proposed to fulfill the standard information of annex IX on long-term toxicity to fish. This WoE does not include any experimental, in vivo, vitro or silico study, which is the reason why no RSS is provided.
According to the attached Weight of evidence, a worst-case long-term NOEC/EC10 of 1.18 mg/L for fish is considered as the key value for the purposes of environmental classification and quantitative risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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