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Description of key information

LD50 (oral): > 10000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
10 000 mg/kg bw

Additional information

In a pre GLP study comparably performed according to OECD 401 with acceptable restrictions groups of 5 rats per sex and dose were administered with 10,000 mg/kg bw of the test substance (vehicle: aqueous emulsion containing 0.5% carboxy methylcellulose). The dose volume was 20 mL/kg bw (= maximum 4.2 mL/ animal). The acute LD50 for male and female rats is > 10,000 mg/kg. No clinical signs or abnormal necropsy findings were observed (BASF AG, 1978).

Justification for classification or non-classification

Classification for acute toxicity is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.

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