Registration Dossier
Registration Dossier
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EC number: 221-499-3 | CAS number: 3121-61-7
Endpoint summary
Administrative data
Description of key information
Additional information
The substance exhibits an adsorption coefficient (log Koc) and partition coefficient (log Kow) below 5 and is readily biodegradable. Moreover, the substance is not very acutely toxic in the aquatic compartment (EC/LC50 for fish, Daphnia and algae above 1 mg/L). In case of exposure to soil, the substance is expected to rapidly degrade, thus the hazard to terrestrial organisms is considered to be negligible. Hence, the Equilibrium Partitioning Method is sufficient to calculate the PNEC values for the terrestrial compartment according to the “Guidance on information requirements and chemical safety assessment, Chapter R.7c: Endpoint specific guidance”, Section 7.11.6 Integrated Testing Strategy for Effects on Terrestrial Organisms (ECHA 2008).
Furthermore, one study on the toxicity to soil microorganisms is available from a structural analogue, methyl acrylate (CAS 96 -33 -3), which was considered suitable for read-across. This study on carbon transformation was conducted according to OECD 217 and GLP, glucose-induced respiration rates were measured. A 28d-EC50 value of > 1000 mg/kg dw was determined based on nominal concentrations (BASF SE, 2010).
In accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 read-across to another structurally related analogue substance was conducted. Read-across data from methyl acrylate (CAS 96 -33 -3) were used, which was considered suitable for read-across. Due to structural and property similarities with the tested analogue substance, it can be concluded that the above result also applies to 2-methoxyethyl acrylate (CAS 3121-61-7). For details see analogue justification in the overall summary of Chap 6.1 and in Chapter 13 of the Technical Dossier.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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