Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-603-6 | CAS number: 97-72-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
8.1. Assessment of PBT/vPvB Properties - Comparison with the Criteria of Annex XIII
8.1.1. Persistence Assessment
Due to the results from chapter 4.1 Degradation showing the substance to be readily biodegradable, the substance is not considered to be persistent (not P) and not very persistent (not vP) in the environment.
8.1.2. Bioaccumulation Assessment
Due to the results from chapter 4.3 Bioaccumulation the substance is not bioaccumulative (not B) and not very bioaccumulative (not vB) based upon a low log Kow value (<3.0) and model predictions.
8.1.3. Toxicity Assessment
Due to the results of the aquatic toxicity studies (see chapter 7.1. Aquatic compartment including sediment), the
substance is not toxic (not T).
The relevant mammalian toxicity studies (see chapter 5. Human Health Hazard Assessment), show only low
toxicity for isobutyric acid in acute oral and dermal studies.
No toxicity for long-term endpoints results from the respective studies, so according to Annex XIII, REACh the substance is not toxic.
8.1.4. Summary and overall Conclusions on PBT or vPvB Properties
Hydrolysis studies document that isobutyric anhydride rapidly and completely hydolyses to isobutyric acid in the environment and in biological systems. Isobutyric acid data indicates that none of the criteria for PBT or vPvB have been met, thererfore isobutyric anhydride is also not considered to be a PBT or vPvB substance.
8.2. Emission Characterisation
Because the substance does not fulfill the PBT and vPvB criteria, no emission characterization is performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
