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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Isobutyric acid log BCF = 0.5 (estimated based on an experimental log Pow of 1.1) (ECT, 2009)

Key value for chemical safety assessment

Additional information

Hydrolysis studies show that isobutyric anhydride added to water rapidly converts to isobutyric acid. Thererfore, isobutyric acid data is being used by read across for most environmental fate and ecotox endpoints.

In accordance with column 2 of Annex IX, the study does not need to be conducted if the substance has a low potential for bioaccumulation. The log Kow of 1.1 for isobutyric acid (OXEA, 2009) indicates a low potential for bioaccumulation. Therefore and for reasons of animal welfare a fish study is not performed.

The log BCF of isobutyric acid was estimated to be 0.5 (BCF = 3.162) using the program BCFBAF v3.00 (Part of US EPA EPI Suite v4.00). In addition, a log BAF (upper trophic) of 0.31 (BAF = 2.06) was calculated using the method of Arnot-Gobas (ECT, 2010). The low BCF/BAF values indicate a low potential of isobutyric acid for bioaccumulation in aquatic organisms.