Registration Dossier
Registration Dossier
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EC number: 256-350-1 | CAS number: 48076-38-6
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
According to REACH Annex IX section 9.3.2
column 2 a study on bioaccumulation can be waived if no direct or
indirect exposure to the environment is expected. At production sites,
the esters are handled in closed systems for polymerisation. Diffuse
releases into the environment from residual monomers in the polymeric
products are not of concern due to the extremely low vapour pressure of
the substances. Thus no test is required.
The bioaccumulation potential of the test substance was calculated to be 2.91/(106.8)
L/kg or log BCF = 0.463 using the EPA Epiwin (v.4.11) software.
According to Annex XIII a substance does not fulfils the Bioaccumulation
criterion (B-) when the bioconcentration factor (BCF) is lower than
2000, therefore a test for bioaccumulation: aquatic/sediment does not
need to be conducted.
Key value for chemical safety assessment
Additional information
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of tetradecyl acrylate (Q)SAR results were used for assessment of bioaccumulation.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Further experimental studies on bioaccumulation are not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
