Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 417-790-1 | CAS number: 78418-01-6
Endpoint summary
Administrative data
Description of key information
Additional information
Two acute studies (on fish and daphnia) and one on algae were available for this substance.
First, in the 96 -hour acute toxicity study on zebrafish (Brachydanio rerio), conducted under GLP and following OECD guideline, the LC50(96h) were comprised between 10 to 16 mg/L.
Then, in the 48 -hour acute toxicity study on Daphnia magna, conducted under GLP and following OECD guideline, the EC50(48h) = 26.1 mg/L.
Finally, the 72 -hour acute toxicity study on green algae (Scenedesmus subscpicatus), conducted under GLP and following OECD guideline, the EC50(72h) = 160 mg/L
Therefore, based on the results of these studies, the most sensitive species is zebrafish.
The LC50 is calculated by regression analysis (assuming LC0 of 10 mg/L and LC100 of 16 mg/L). This gives a LC50 of 13 mg/L.
The LC50 value from fish will be used to PNEC calculation.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
