Registration Dossier
Registration Dossier
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EC number: 219-348-1 | CAS number: 2421-28-5
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The BCF was estimated at 18.13 L/kg wet-wt based on the modeled log Kow of 3.30 using the U.S. Environmental Protection Agency EPI Suite Program. However, due to rapd hydrolysis of less than 12 hours in the aquatic environment, there is a data waiver.
Key value for chemical safety assessment
- BCF (aquatic species):
- 18.13 L/kg ww
Additional information
In the supporting study entitled “Estimation of the Partition Coefficient (KOWWIN), Vapour pressure (Antoine method), Solubility in water (WSKOW), Adsorption/Desorption Coefficient (KOCWIN), Henry constant (HENRYWIN) and other parts with EPIWIN 4.0 suite of 1,3 -Isobenzofurandione, 5,5'-carbonylbis- (BTDA) CAS-No.: 2421 -28 -5 in Dependence on the pH Value by Quantitative Structure Activity Relationship(QSAR-Method = Calculation)” (report no. 2012 -0428 -DKB), the BCF was estimated at 18.13 L/kg wet-wt based on the modeled Log Kow of 3.30 using the U.S. Environmental Protection Agency EPI Suite Program. However, since the study entitled “Statement on 3,3’,4,4’-Benzophenonetetracarboxylic dianhydride: Hydrolysis as a Function of pH: according to OECD Guideline No. 111 (2004) and Council Regulation (EC) No. 440/2008, Method C.7” performed at Dr.U.Noack-Laboratorien Sarstedt, Germany, determined that the hydrolytic half life, at ambient temperature, is less than 10 minutes there is a data waiver based on a rapid hydrolysis. In addition, the hydrolysis product BTA (CAS No. 2479 -49 -4), the hydrolysis product of BTDA, also has a low log Kow (equal to 1.3) and is therefore not considered to be bioaccumulative.
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