Registration Dossier
Registration Dossier
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EC number: 203-157-5 | CAS number: 103-90-2
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- No information
- Year:
- 1 969
- Bibliographic source:
- Gigiena i Sanitariya.For English translation, see HYSAAV.(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-Volume(issue)/page/year: 34(10),36,1969
- Reference Type:
- review article or handbook
- Title:
- RTECS NUMBER : AM4375000
- Author:
- RTECS database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-1936-Volume(issue)/page/year:34(10),36,1969
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Phenacetin
- EC Number:
- 200-533-0
- EC Name:
- Phenacetin
- Cas Number:
- 62-44-2
- IUPAC Name:
- N-(4-ethoxyphenyl)acetamide
- Details on test material:
- - Name of test material (as cited in study report): phenacetin
- Substance type: Organic
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 33 900 mg/m³ air
- Based on:
- test mat.
- Remarks on result:
- other: Other details not available
- Mortality:
- Lethal concentration, 50 percent kill
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute inhalation median lethal concentration (LC50) of phenacetin in mouse was found to be 33900 mg/m³ air. Acute toxicity of phenacetin to mouse by the inhalation route indicates that phenacetin does not exhibits acute toxicity by the inhalation route within the dose level mentioned in the study.
- Executive summary:
The acute inhalation median lethal concentration (LC50) of phenacetin in mouse was found to be 33900 mg/m³ air. Acute toxicity of phenacetin to mouse by the inhalation route indicates that phenacetin does not exhibits acute toxicity by the inhalation route within the dose level mentioned in the study.
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