Registration Dossier
Registration Dossier
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EC number: 500-165-3 | CAS number: 66455-14-9 1 - 2.5 moles ethoxylated
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP Guideline study with acceptable restrictions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 979
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Deviations:
- yes
- Remarks:
- Occlusive dressing, 24h exposure.
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Alcohols, C12-13, ethoxylated
- EC Number:
- 500-165-3
- EC Name:
- Alcohols, C12-13, ethoxylated
- Cas Number:
- 66455-14-9
- Molecular formula:
- UVCB: Not available
- IUPAC Name:
- Alcohols, C12-13, ethoxylates, 1-2.5 EO
- Details on test material:
- - Name of test material (as cited in study report): primary alcohol ethoxylate (C12-C13)
- Ethoxylation degree: 2
- Analytical purity: No data
- Lot/batch No.: No data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- According to Guideline.
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- unchanged (no vehicle)
- Duration of exposure:
- 24 h
- Doses:
- 1000, 2000, 4000 mg/kg bw
- No. of animals per sex per dose:
- 4
- Control animals:
- not required
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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