Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-755-6 | CAS number: 110-30-5
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- short-term repeated dose toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 407 (Repeated Dose 28-Day Oral Toxicity Study in Rodents)
- GLP compliance:
- yes
- Remarks:
- MHLW, Japan
Test material
- Reference substance name:
- N,N'-ethylenedi(stearamide)
- EC Number:
- 203-755-6
- EC Name:
- N,N'-ethylenedi(stearamide)
- Cas Number:
- 110-30-5
- Molecular formula:
- C38H76N2O2
- IUPAC Name:
- N,N'-ethylenedi(stearamide)
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Crj: CD(SD)
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- corn oil
- Duration of treatment / exposure:
- 28d
- Frequency of treatment:
- once daily (7 days/week)
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0, 300 and 1000 mg/kg/day
Basis:
nominal in diet
- No. of animals per sex per dose:
- Group size: 5 animals per sex per dose
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- 1 000 mg/kg bw/day (nominal)
- Based on:
- test mat.
- Sex:
- male/female
- Basis for effect level:
- other: 28d test
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
No effects were seen, in any of the treament groups and in either sex
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
