Registration Dossier
Registration Dossier
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EC number: 203-755-6 | CAS number: 110-30-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vivo
Link to relevant study records
- Endpoint:
- in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
- Remarks:
- Type of genotoxicity: chromosome aberration
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Guideline:
- OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
- GLP compliance:
- no
- Type of assay:
- micronucleus assay
- Species:
- mouse
- Sex:
- not specified
- Genotoxicity:
- negative
- Toxicity:
- not specified
- Conclusions:
- Interpretation of results (migrated information): negative
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
Bacterial reverse mutation assay OECD471 (Ames test): negative
In vitro mammalian chromosome aberration (chinese hamster lung cells) OECD473: negative
In vivo miconucleus assay (chromosome aberration) in mouse OECD 474: negative
Justification for classification or non-classification
In view of the above results a classification for genetoxicity is not required
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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