Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: oral
Remarks:
other: no data
Type of information:
other: no data
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source from the IUCLID dataset.

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID dataset
Author:
WP Mannheim GmbH
Year:
1994
Bibliographic source:
substance 81-84-5

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Remarks:
secondary source

Test material

Constituent 1
Chemical structure
Reference substance name:
Naphthalene-1,8-dicarboxylic anhydride
EC Number:
201-380-2
EC Name:
Naphthalene-1,8-dicarboxylic anhydride
Cas Number:
81-84-5
Molecular formula:
C12H6O3
IUPAC Name:
3-oxatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaene-2,4-dione
Details on test material:
same with section 1.1-1.4

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: feed
Vehicle:
not specified
Analytical verification of doses or concentrations:
not specified

Results and discussion

Effect levels

Dose descriptor:
other:
Basis for effect level:
other: In 90 day feeding trials no ill-effect was noted for rats and dogs receiving 500 mg/kg diet
Remarks on result:
not measured/tested
Remarks:
Effect level not specified (migrated information)

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion