Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: oral
Remarks:
other: no data
Type of information:
other: no data
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source from the IUCLID dataset.

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID dataset
Author:
WP Mannheim GmbH
Year:
1994
Bibliographic source:
substance 81-84-5

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Remarks:
secondary source

Test material

Constituent 1
Chemical structure
Reference substance name:
Naphthalene-1,8-dicarboxylic anhydride
EC Number:
201-380-2
EC Name:
Naphthalene-1,8-dicarboxylic anhydride
Cas Number:
81-84-5
Molecular formula:
C12H6O3
IUPAC Name:
3-oxatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaene-2,4-dione
Details on test material:
same with section 1.1-1.4

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: feed
Vehicle:
not specified
Analytical verification of doses or concentrations:
not specified

Results and discussion

Effect levels

Dose descriptor:
other:
Basis for effect level:
other: In 90 day feeding trials no ill-effect was noted for rats and dogs receiving 500 mg/kg diet
Remarks on result:
not measured/tested
Remarks:
Effect level not specified (migrated information)

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion