Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian germ cell study: gene mutation
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source from the IUCLID dataset.

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID dataset
Author:
WP Mannheim GmbH
Year:
1985
Bibliographic source:
substance 81-84-5

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Remarks:
secondary source
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Naphthalene-1,8-dicarboxylic anhydride
EC Number:
201-380-2
EC Name:
Naphthalene-1,8-dicarboxylic anhydride
Cas Number:
81-84-5
Molecular formula:
C12H6O3
IUPAC Name:
1H,3H-benzo[de]isochromene-1,3-dione
Details on test material:
same with section 1.1-1.4

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Vehicle:
no data

Results and discussion

Test results
Sex:
not specified
Genotoxicity:
negative

Applicant's summary and conclusion